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髓源抑制性细胞的研究进展 被引量：7

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摘要 免疫抑制是肿瘤患者治疗疗效差、预后不理想的重要原因之一。肿瘤免疫抑制不仅与恶性肿瘤的发生、发展有关,而且与肿瘤免疫治疗疗效不佳及治疗后复发密切相关。因而改善或逆转免疫抑制对成功治疗肿瘤具有十分重要的意义。多种免疫细胞成分,如髓源抑制性细胞（myeloid-derived suppressor cells,MDSCs）、肿瘤相关巨噬细胞（tumor-associated macrophage,TAM）、调节性T细胞（regulatory T cells,
作者 朱晓青 苏龙 高素君
机构地区 吉林大学白求恩第一医院肿瘤中心
出处 《中国实验诊断学》 2016年第3期511-512,共2页 Chinese Journal of Laboratory Diagnosis
关键词 肿瘤免疫治疗 抑制性细胞 免疫抑制 巨噬细胞 免疫细胞 MYELOID MACROPHAGE SUPPRESSOR 获得性免疫应答 树突细胞
分类号 R730.5 [医药卫生—肿瘤]
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参考文献20

  • 1Ostrand-Rosenberg S. Myeloid-derived suppressor cells: more mechanisms for inhibiting antitumor immunity[J]. Cancer Im- munol lmmunother, 2010,59(10) :1593.
  • 2Haile LA, Greten TF, Korangy F. Immune suppression: the hall- mark of myeloid derived suppressor cells[J]. Immunol Invest, 2012,41(6-7) :581.
  • 3Talmadge JE,Gabrilovich DI. History of myeloid-derived suppres- sor cells[J]. Nat Rev Cancer,2013,13(10):739.
  • 4万琳,胡鑫,赵贤贤,李晓燕,李卓娅,尹丙姣.髓样抑制细胞免疫抑制机理的研究[J].中国免疫学杂志,2010,26(1):17-22. 被引量：4
  • 5Gabrilovich DI, Nagaraj S. Myeloid-derived suppressor cells as regulators of the immune system[J]. Nat Rev Immunol, 2009,9 (3):162.
  • 6Youn JI, Nagaraj S, Collazo M, et al. Subsets of myeloid-derived suppressor cells in tumor-bearing mice[J]. J Immunol,2008,181 (8) :5791.
  • 7Montero A J, Diaz-Montero CM, Kyriakopoulos CE, et al. Myeloid- derived suppressor cells in cancer patients: a clinical perspective [J]. J Immunother,2012,35(2) : 107.
  • 8Filipazzi P, Huber V, Rivoltini L. Phenotype, function and clinical implications of myeloid-derived suppressor cells in cancer pa- tients[J]. Cancer Immunol Immunother,2012,61(2):255.
  • 9Nagaraj S,Gabrilovich DI. Myeloid-derived suppressor cells in hu- man cancer[J]. Cancer J ,2010,16(4) :348.
  • 10Lu T, Ramakrishnan R, Altiok S, et al. Tumor-infiltrating mye- loid cells induce tumor cell resistance to cytotoxic T cells in mice [J]. J Clin Invest,2011,121(10) :4015.

二级参考文献31

  • 1Sauter B, Alert M L, Loise Francisco et al. Consequences of cell death : exposure to necrotic tumor cells, but not primary tissue cells or apoptotic cells, induces the maturation of immunostimulatory dendritic cells[ J]. J Exp Med,2000; 191(3) :423-434.
  • 2Thumher M, Radmayr C, Ramoner R et al. Human renal-cell carcinoma tissue contains dendritic cells[ J]. lnt J Cancer, 1996;67( 1 ) : 1-7.
  • 3Almand B, Resser J R, Lindman Bet al. Clinical significance of defective dendritic cell differentiation in cancer[J]. Clin Cancer Res,2000;6 (5) : 1755-1766.
  • 4Wojas K,Tabarkiewicz J, Jankiewicz Met al . Dendritic cells in peripheral blood of patients with breast and lung cancer-a pilot study[J]. Folia Histochem Cytobiol,2004;42( 1 ) :45-48.
  • 5Levitsky H I, Montgomery J, Ahmadzadch M et al. immunization with granulocyte-m,acmphage colony-stimulating factor-transduced, but not B7-1-transduced, lymphoma cells primes idiotype-specific T cells and generates potent systemic antitumor immunity[J]. J Immunol, 1996; 156 (10) : 3858-3865.
  • 6Firm O J. Cancer vaccines:between the idea and the reality [J] .Nat Rev Immunol,2003; 3(8) :630-641.
  • 7Durra G P, Bruce A T, Lkeda H etal. Cancer immunoediting: from immunosurveillance to tumor escape [ J ]. Nat Immunol, 2002; 3 ( 11 ) : 91-98.
  • 8PardoU D. Does the immune system see tumors as foreign or self ? [ J ]. Annu Rev Immunol, 2003; 21 : 807-839.
  • 9Yang R C,Cai Z, Yuan William H et al. CDS0 in irmmme suppresssion by mouse ovarian carcinoma-associated Gr-1 ^+CD11b^+ myeloid cells [ J ]. Cancer Res,2006;66(13) :6807-6815.
  • 10Vakkila J, Lotze M T. Inflammation and necrosis promote tumor growth [J]. Nat Rev Immunol,2004;4(8):641-648.

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中国实验诊断学
2016年 第3期

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