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IgA1分子糖基化异常在IgA肾病发病机制中的研究进展 被引量:6

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摘要 原发性IgAN是世界范围内最常见的原发性肾小球疾病,是终末期肾病(ESRD)重要病因之一。Berger和Hinglais于1968年首次描述IgAN的病理特点,其肾小球系膜区沉积着含IgA1的免疫复合物[1]。目前IgAN发病机制尚未阐明,但已有诸多研究证实IgA1分子糖基化的异常及免疫复合物的形成在IgAN发病机制中起重要作用[2]。
出处 《中国实验诊断学》 2016年第3期513-516,共4页 Chinese Journal of Laboratory Diagnosis
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参考文献35

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二级参考文献40

  • 1张宏.IgA肾病的分子遗传学研究[J].中华肾脏病杂志,2005,21(11):641-644. 被引量:12
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