早产儿控温湿化常压氧疗的疗效观察

Clinical effect observation on treatment of premature infants with temperature control and humidity

目的探讨早产儿控温湿化常压氧疗的临床治疗效果及安全性,寻求更适合的早产儿氧疗方式。方法筛查符合条件的早产儿80例,随机分为两组,治疗组40例,对照组40例,治疗组采用可控温湿化及可调节氧浓度的空氧混合仪给予常压氧疗,而对照组采用传统的仅通过湿化瓶进行简单的湿化且不可加温及调节氧浓度的常压氧疗,观察两组氧疗法对早产儿的心率、呼吸、需氧浓度、氧疗时间及并发症的治疗等指标的影响及差异。结果与对照组比较,治疗组氧疗浓度要求低于对照组,氧疗时间、住院时间均明显缩短(P<0.01),治疗48小时后其体温、心率、呼吸、PO_2、PCO_2等指标变化存在差异(P<0.01),且早产儿其它并发症的治疗效果好(P<0.01)。结论控温湿化的空氧混合仪氧疗治疗早产儿相比传统湿化氧疗安全、有效,能更好的提高早产儿生存质量。

Objective To investigate the clinical effect and safety of the treatment of premature infants with temperature control and humidity,and to find a more suitable method for oxygen therapy in premature infants. Methods 80 cases of premature infants were randomly divided into 2 groups,treatment group 40 cases,control group 40 cases,the treatment group was treated with controlled temperature and humidity,and the control group was treated with traditional method. The effect and difference of two groups of oxygen therapy on heart rate,respiration,oxygen therapy time and complications were observed. Results Compared with the control group,the oxygen concentration of treatment group was lower than the control group,oxygen therapy time,length of hospital stay were significantly shortened（ P〈0. 01）,48 hours after treatment,the body temperature,heart rate,respiratory,PO2,PCO2 and other indicators were significantly different（ P〈0. 01）,and premature infants with other complications of treatment were better（ P〈0. 01）. Conclusions Oxygen therapy in the treatment of premature infants with temperature controlled humidification of air oxygen mixture is safe and effective,and can better improve the quality of life of premature infants.