临床药师会诊一例难治性感染患者的药物治疗方案分析

Analysis on the Therapeutic Scheme for One Case of Refractory Infections with Clinical Pharmacists' Consultation

目的探讨临床药师参与临床药物治疗的实践方法。方法患者男,88岁。因"劳力性心累4年,咳嗽、咯痰10 d,突发吐词不清4 h"于2013年11月22日入院。诊断:脑梗死;肺部感染。因肺部感染反复发生且控制不佳,于2014年2月19日请临床药师会诊。临床药师利用药物治疗方案分析方法,参与该例难治性感染患者治疗方案制定和调整。结果调整治疗方案后,患者呼吸频率、体温、白细胞计数、中性粒细胞比例均恢复正常,痰量明显减少,痰培养阴性,肺部体征和影像明显改善,取得了明显疗效。结论临床药师应重视对药物治疗方案的分析,提高难治性感染患者诊疗效果。

Objective To discuss the practical methods of clinical drug therapy with clinical pharmacists＇ participation. Methods The patient was male and at the age of 88. Because of ＂exertional heart tiredness for 4 years, coughing sputum for 10 days, and sudden inarticulate condition＂, he was admitted into the hospital on November 22 nd, 2013. The diagnosis was cerebral infarction with pulmonary infection. Clinical pharmacists participated in the consultation on February 19 th, 2014 because the uncontrollable repeated pulmonary infection. By analyzing the therapeutic scheme, clinical pharmacists made and adjusted the treatment scheme for one patient with refractory infections. Results After the treatment scheme was adjusted, several laboratory test results of the patient returned to normal, including respiratory rate, body temperature, white blood cell count and neutrophils. Sputum volume decreased obviously and sputum culture was negative. Lung signs and image were significantly improved. Conclusion Clinical pharmacists should pay more attention to the analysis of the clinical therapeutic scheme to improve therapeutic efficacy for patients with refractory infections.