浙江省瑞安地区学龄期儿童前房深度与屈光状态的相关研究

Correlation between anterior chamber depth and refractive status in schoolchildren in Ruian of Zhejiang province

目的分析学龄期儿童前房深度（ACD）对屈光状态的影响。方法横断面研究。在浙江省瑞安地区随机选取小学一年级至六年级各2个班共513名学生（1025眼），年龄为7～14岁。在瑞安市人民医院门诊进行相关眼科检查，包括裂隙灯显微镜、眼屈光度、IOLMaster检查等，记录等效球镜度（SE）、眼轴长度（AL）、前房深度（ACD）、年龄等相关基本信息。通过线性混合效应模型来分析ACD、AL与年龄、屈光度的关系。结果7～14岁学龄期儿童，平均AL为（23．68±1．09）mm，平均ACD为（3．48±0．26）mm，平均屈光度为-1．06（-11．37～＋6．25）D；ACD与SE呈负相关（β=-0．048，P〈0．01）。正视眼和近视眼的ACD和AL存在差异。结论在学龄期儿童，ACD与年龄相关，随着年龄增长，ACD有轻微加深趋势。ACD影响屈光状态，近视眼的ACD较正视眼更长。

Objective To investigate the correlation between anterior chamber depth （ACD） and refractive status in schoolchildren. Methods 1 025 eyes of 513 students aged between 7 and 14 who reside in Ruian in Zhejiang province were randomly selected for a cross-sectional study. Subjective refraction, slit lamp examination and IOLMaster measurements were performed in an outpatient room. Spherical equivalence （SE）, anterior chamber depth （ACD）, axial length （AL） and age were registered and the correlation between ACD, SE and age, as well as the correlation between AL and SE, were analyzed with mixed-effects models by SPSS 22.0. Results Average AL, ACD and SE were 23.68＋ 1.09 mm, 3.48±0.26 mm and -1.06（-11.37-＋6.25）D, respectively. ACD was correlated negatively with SE （β=-0.048, P〈0.01）. Both ACD and AL were significantly higher in myopic eyes than in emmetropic eyes. Conclusion ACD differed with age and refractive status in school-age students. Older students with myopia have a deeper ACD than younger students with emmetropia.