SPECT/CT融合图像与全身骨显像对骨转移瘤诊断的价值分析

The Diagnosis Value Analysis of SPECT/CT Fusion Images and Whole Body Bone Imaging for Bone Metastases

目的探讨SPECT/CT融合图像与全身骨显像(whole-body bone scintigraphy,WBBS)对骨转移瘤的价值比较。方法回顾性分析我院80例可疑肿瘤骨转移性病变患者行WBBS及SPECT/CT断层图像融合,所有结果都通过病理或进一步随访等方式确诊。分别计算并比较两种结果对病例及病灶诊断的灵敏度、特异度、阳性预测值、阴性预测值、正确诊断百分率。结果 80例患者骨转移61例,19例为良性病例,258处病灶中,骨转移202处,良性病灶为56处。WBBS对病例及病灶诊断的灵敏度分别为82%和89.1%,特异度分别为42.1%和31.7%,阳性预测值分别为82%和84.7%,阴性预测值分别为42.1%和40.6%,准确率72.5%和78.1%。SPECT/CT对病例及病灶诊断的灵敏度分别为98.4%和98%,特异度分别为52.6%和76.8%,阳性预测值分别为87%和93.8%,阴性预测值分别为90.9%和91.5%,准确率为87.5%和83.4%。两组数据均经过χ2检验,P<0.05。结论在骨转移瘤的诊断中,SPECT/CT融合图像较WBBS明显更具有诊断价值。

Objective To investigate the comparison of SPECT/CT fusion image and whole body bone imaging（whole-body ipads scintigraphy, WBBS） in bone metastasis value. Methods retrospective analysis of 80 cases of suspected tumor bone metastatic disease underwent whole-body bone imaging and SPECT/CT fault image fusion in our hospital, all the results are confirmed by pathology and further follow-up and otherwise. Calculate and compare the two results of cases and lesions diagnosed degree of sensitivity, specific percentage, positive predictive value, negative predictive value, the correct diagnosis. Results 80 patients, 61 cases of bone metastases, 19 cases were benign, 258 lesions, the bone metastases, 202 benign lesions is 56. The sensitivity of WBBS for diagnosis of patients and lesions were 82% and 89.1%, the specificity was 42.1% and 31.7% respectively, the positive predictive value were 82% and 84.7%, and negative predictive values were 42.1% and 40.6%, the percentage of correct diagnosis was 72.5% and 78.1%. The sensitivity of SPECT/CT for diagnosis of patients and lesions were 98.4% and 98%, the specificity was 52.6% and 76.8% respectively, the positive predictive value were 87% and 93.8%, and negative predictive values were 90.9% and 91.5%, the percentage of correct diagnosis was 87.5% and 83.4%.Both sets of data after the χ^2 test, P0.05. Conclusion In the diagnosis of bone metastasis, SPECT/CT fusion image is more obvious than WBBS has diagnostic value.