高血压患者动态脉压指数与冠状动脉病变的相关性分析

Correlation Analysis between Ambulatory Pulse Pressure Index and Coronary Artery Lesions in Hypertension Patients

目的探讨高血压患者动态脉压指数(Ambulatory pulse pressure index,PPI)与冠状动脉病变的关系。方法选取我院高血压患者"226例,根据冠脉造影对冠脉狭窄程度进行分组,其中冠脉狭窄程度≥50%纳入病例组(126例),而冠脉狭窄程度<50%纳入对照组(100例),采用动态血压检测仪测定脉压指数。结果病例组PP与PPI明显高于对照组,差异具有统计学意义(P<0.05),随着PPI增加,冠状动脉病变支数逐渐增加,不同PPI患者冠状动脉病变支数比较差异具有统计学意义(P<0.05),Spearman相关性分析显示,PPI与冠状动脉病变相关性最显著(r=0.432,P<0.05)。结论高血压患者动态脉压指数与冠状动脉狭窄程度及其支数具有紧密的关系,PPI有助于更好反映冠状动脉病变程度。

Objective To investigate the relationship between ambulatory pulse pressure index （PPI） and coronary artery lesions in hypertension patients. Methods A total of 226 hypertension patients in our hospital were selected and divided based on coronary angiography and severity of coronary stenosis into the case group （126 cases, coronary artery stenosis ≥50% ） and the control group （ 100 cases, coronary stenosis 〈 50% ）, pulse pressure index were measured by ambulatory blood pressure. Results PP and PPI of the ease group were significantly higher than those of control group, with statistically significant difference （ P 〈 0. 05 ）. With the in- crease of PPI, coronary artery lesion counts gradually increased, with statistically significant difference （ P 〈 0. 05 ）. Spearman corre- lation analysis showed that, PPI was most significantly correlated with coronary artery lesions severity （ r = 0. 432, P 〈 0. 05 ）. Con- clusion Hypertension ambulatory pulse pressure index is closely related to coronary artery stenosis and count, and PPI is helpful to reflect the severity of coronary artery lesions.