重症医学国外研究热点聚类分析

Cluster analysis of most popular subjects for research in critical care medicine in foreign countries

目的：从文献分析角度把握国外重症医学主要研究内容，为国内开展重症医学研究提供借鉴。方法采用双向聚类的文献计量分析方法，通过检索美国国立医学图书馆PubMed数据库收录的2004年到2015年相关重症医学研究方面的文献进行分析，并采用信息分析可视化方法揭示学科研究热点。结果2004年1月1日至2015年11月8日国外重症医学研究热点主要集中在8个方面，包括：重症患者的血糖控制、重症患者急性肾损伤（AKI）和肾脏替代治疗（RRT）、重症患者营养支持﹑重症加强治疗病房（ICU）对降低病死率的影响﹑危重患者病情评估﹑抗菌药物耐药研究﹑重症患者生活质量评估以及重症患者家庭康复与护理。汇总所有有关重症医学的文献可以看出，重症医学自成立以来一直处于稳步增长的态势，其中美、欧、日是重症医学研究最为发达的地区；形成了4个主要研究关系网，分别为关于重症患者血糖控制﹑循环功能监测﹑营养支持和AKI方面的研究。结论2004年至2015年国外重症医学研究热点主要集中在血糖控制、循环功能监测、营养支持和AKI4个方面。

Objective To collect the main contents of research in critical care medicine in foreign countries with the purpose of providing references for domestic research. Methods A two-way clustering analysis of foreign literature in PubMed concerning critical care medicine was conducted from 2004 to 2015 in this study, and the subjects of greatest interest were collected through the information visualization analysis pathway. Results Eight areas of most popular interest critical care medicine from January 1st, 2004 to November 8th, 2015 were found： blood sugar control in intensive care unit （ICU）, acute kidney injury （AKI） and renal replacement therapy （RRT）, nutritional support, the impact of ICU practice on reducing mortality, the assessment of critical patients, study of antibiotic resistance, the assessment of the life quality of critically ill patients, and home care and the rehabilitation of critically ill patients. According to the related literature, research in the field of critical care medicine has been growing steadily. USA, Japan, and Europe are the most developed countries or area in the field of critical care medicine. The four major research networks concerning research in critical care medicine were found： the control of blood glucose, monitor of circulatory function, nutritional support, and studies on AKI. Conclusion The most popular topics in research concerning critical care medicine research from 2004 to 2015 were blood glucose control, monitoring of circulatory function, nutritional support and AKI.