长方案降调节后高雌二醇水平获得双胎妊娠的病例分享

A patient with high E_2 level after pituitary down-regulation receiving twin pregnancy under intracytoplasmic sperm injection-embryo transfer treatment——a case report

目的:探讨卵胞质内单精子显微注射-胚胎移植(ICSI-ET)长方案降调节后高雌二醇(E_2)水平的治疗方案。方法:对1例ICSI-ET长方案降调节后高E_2水平获得双胎妊娠的病例进行分析并总结经验。结果:通过适时启动超促排卵,患者获卵8枚,形成可用胚胎数3个,移植胚胎后成功获得双胎妊娠。结论:对于长方案降调节后E_2水平仍高的患者应根据其具体情况制定个体化的治疗方案。

Objective： To report a case of a patient with high E2 level after pituitary down-regulation receiving twin pregnancy, and to discuss the treatment options for these patients. Methods： The patient received intracytoplasmic sperm injection-embryo transfer （ICSI-ET） treatment with long gonadotrophin-releasing hormone agonist （GnRHa） protocol. We reported the case and reviewed the articles. Results： With the opporamely start of hyperstimulation, the patient got appropriate number of oocytes and embryos, and received twin pregnancy finally. Conclusion： For the patients with high E2 level after down-regulation, we should have individualized treatments according to their specific conditions.