摘要
目的探讨体外受精-胚胎移植(IVF-ET)结局与患者职业、学历及围孕期居住地的关系。方法回顾南方医院生殖中心2010年1月~2014年6月首次IVF-ET助孕患者(n=3998)以及同期所有围产儿临床资料(n=3064)。了解不同IVF-ET结局与患者职业、学历及居住地的关系。结果与本中心总体水平相比,女方务农患者早期流产风险升高(OR=4.319,P=0.047)。男女双方职业与学历与IVF-ET异位妊娠存在相关性。围产儿出生缺陷发生率为2.1%。深圳市出生缺陷发生率较高(5.5%),但与广东省其他地区差异无统计学意义(P〉0.05)。结论患者职业及学历对IVF-ET助孕结局有一定影响。积极开展卫生宣教和产前检查十分必要。
Objective To investigate the associations of occupational, educational and residential factors with the outcomes of in vitro fertilization-embryo transfer(IVF-ET). Methods A retrospective analysis was conducted among 3998 patients undergoing the first treatment with IVF-ET and 3064 perinatal infants in our center between January, 2010 and June, 2014. The relation of the patients' occupation, educational background, and residence registry with IVF- ET outcomes was analyzed. Results The risk of abortion in the first trimester was significantly higher in female patients engaged in agriculture(OR=4.319, P=0.047).Occupation and educational background of the patients and their spouse were related with the incidence of ectopic pregnancy following IVF-ET. The total incidence rate of perinatal birth defects was 2.1% in this cohort, and was the highest in Shenzhen(5.5%) but this difference was not statistically significant(P0.05). Conclusion The patients' occupation and educational background are related with the outcomes of IVF-ET, suggesting the importance of health education and prenatal examination.
出处
《南方医科大学学报》
CAS
CSCD
北大核心
2016年第1期44-49,共6页
Journal of Southern Medical University
基金
国家科技支撑计划项目(2013BAI12B00)~~
关键词
体外受精-胚胎移植结局
职业
学历
居住地
in vitro fertilization-embryo transfer
outcome
occupation
educational background
residence