益生菌在维持治疗溃疡性结肠炎中的效果研究

Study on Probiotics Effect in Maintenance Treatment of Ulcerative Colitis

目的探究溃疡性结肠炎患者选择益生菌维持治疗的方法和效果。方法选取2014年7月~2015年9月收治的76例溃疡性结肠炎患者进行治疗,随机分组,实验组40例选择美沙拉嗪和益生菌胶囊的综合治疗,对照组36例患者仅采用美沙拉嗪的治疗,比较患者治疗后身体症状的缓解和不良反应。结果对照组患者治疗的总有效率为83.33%,实验组治疗的总有效率为95.0%,和对照组患者相比,实验组患者得到更加显著的治疗效果,差异有统计学意义（P〈0.05）。结论溃疡性结肠炎患者选择益生菌维持治疗,可以提高患者的治疗效果,加快身体不适症状的缓解,减少不良反应的出现。

Objective Probiotics maintenance treatment method and its effect for ulcerative colitis are to be studied. Methods Chose 76 patients of ulcerative colitis that were treated in hospital from July 2014 to September 2015 and separated them into two groups randomly,40 patients in study group were given mesalazine combined with probiotics capsule treatment,while 36 patients in control group were given mesalazine medication treatment only,and then observed and compared patients＇ symptoms recovery conditions and side-effect incidence between two groups. Results Patients＇ treatment efficacy in control group was 83.33% and it was 95.0% in study group,the treatment efficacy was much more favorable in study group,there was a differential between two groups and such a differential had statistic value（P〈0.05）. Conclusion Probiotics maintenance treatment is of efficiency for ulcerative colitis,it is conducive to increasing treatment efficacy,relieving uncomfortable symptoms and reducing side-effect incidence.