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联合门静脉/肠系膜上静脉切除重建的胰十二指肠切除术治疗胰腺癌疗效分析 被引量:13

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摘要 目的探讨胰十二指肠切除联合门静脉(PV)或肠系膜上静脉(SMV)切除重建治疗胰腺癌的疗效。方法行胰腺癌根治切除的158例患者,按有无联合PV/SMV切除分成两组,无血管切除组99例(对照组),联合PV/SMV切除重建组59例(观察组)。比较分析两组患者的术前、手术和随访资料,重点分析联合PV/SMV切除重建对术后并发症和生存状况的影响。结果两组术前CA199阳性率观察组(83.1%)显著高于对照组(64.6%)(P<0.05)。两组手术时间及手术出血量差异均有统计学意义(均P<0.01)。两组患者围手术期均无死亡病例,各种并发症发生率差异均无统计学意义(均P>0.05)。两组中位生存时间差异无统计学意义(P=0.710)。结论对胰腺癌合并PV/SMV侵犯的患者应严格掌握其手术指证,充分评估其体力状况,如能根治切除有一定价值。
出处 《现代实用医学》 2016年第2期167-170,共4页 Modern Practical Medicine
基金 宁波市肝胆胰肿瘤多学科诊治和转化医学创新团队项目(2013B82010)
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