肺炎支原体抗体C-反应蛋白及血清降钙素原检测在儿童呼吸道医院感染诊断中的应用评价

Evaluation on the Application of Mycoplasma Pneumoniae Antibody C-reactive Protein and Serum Procalcitonin Measurement in the Diagnosis of Children's Respiratory Tract Infection

目的:研究肺炎支原体抗体、C-反应蛋白及血清降钙素原检测在儿童呼吸道医院感染诊断中的应用评价。方法:选择2014年1月至2014年6月我院收治的160例儿童呼吸道感染患者,按其致病病原体的分类将其分为细菌感染组(n=50)、肺炎支原体感染组(n=50)、病毒感染组(n=60)。比较所有患者的一般资料、肺炎支原体抗体(MP-Ig M)、血清降钙素原(PCT)、白细胞计数(WBC)以及C-反应蛋白(CRP)。结果:细菌感染组、肺炎支原体感染组、病毒感染组三组患者的一般资料与基本病情方面相比较无统计学差异(P>0.05)。细菌感染组患者的PCT显著高于肺炎支原体感染组与病毒感染组(P<0.05);细菌感染组患者的CRP与WBC水平也显著高于肺炎支原体感染组与病毒感染组(P<0.05)。细菌感染组、肺炎支原体感染组、病毒感染组的MP-Ig M的阳性率分别为4.00%、96.00%与5.00%,肺炎支原体感染组的MP-Ig M的阳性率显著高于其他两组(P<0.05)。结论:肺炎支原体抗体(MP-IgM)、血清降钙素原(PCT)、C-反应蛋白(CRP)三者的检测对儿童呼吸道医院感染诊断有很大帮助,值得广泛推广使用。

Objective： To evaluate the application of mycoplasma pneumoniae antibody,C-reactive protein and serum procalcitonin measurement in the diagnosis of children＇s respiratory tract infection. Method：160 cases of children with respiratory tract infection in our hospital from January 2014 to June 2014 were selected as the objects in this study. According to the classification of disease pathogens,all the patients were divided into three groups： bacterial infection group（ n = 50）,mycoplasma pneumoniae infection group（ n = 50）and virus infection group（ n = 60）. The comparisons were made about the general information,mycoplasma pneumoniae antibody（ MP-Ig M）,serum procalcitonin（ PCT）,white blood cell count（ WBC） and C-reactive protein（ CPR） among all the patients. Result： There was no significant difference about the general information and basic diseases of patients in three groups（ BI group,MPI group and VI group）（ P〈0.05）. PCT of BI group was significantly higher than that in MPI group and VI group（ P〈0.05）. Also,the levels of CPR and WBC in BI group were much higher than those in MPI group and VI group（ P〈0.05）. In addition,the positive rates of MP-Ig M in the three groups were 4.00%,96.00% and 5.00% respectively. Of all,the positive rate of MP-Ig M in MPI group was dramatically higher than the other two groups（ P〈0.05）. Conclusion： The measurements of mycoplasma pneumoniae antibody（ MP-Ig M）,serum procalcitonin（ PCT） and C- reactive protein（ CPR） showed good effectiveness for diagnosis of children with respiratory tract infection. It is worthy of wide application and promotion.