摘要
糖皮质激素抵抗是指部分个体对糖皮质激素无反应或反应性明显降低。糖皮质激素抵抗能够使外源性糖皮质激素不能达到预期的治疗效果,内源性糖皮质激素不能完全发挥作用,导致患者疾病不断进展。为了更好地认识糖皮质激素抵抗的原理和机制,使临床能够合理应用糖皮质激素,有效识别和避免糖皮质激素抵抗的发生,本文对近年来的相关研究进行综述。
Glucocorticoid resistanance refers to some individual performance for no response to glucocorticoids or reactivity decreased obviously.Glucocorticoid resistance can not achieve the desired therapeutic effect of exogenous glucoeorticoids,and endogenous glucocorticoids can not fully play a role,then results to the progress of disease.In order to better understand the principle and mechanism of glueocorticoid resistance,reasonable application of glucocorticoid in clinic and effective identification and avoidance of glucocortieoid resistance,this paper reviews the relevant research in recent years.
出处
《中国当代医药》
2016年第8期21-23,30,共4页
China Modern Medicine
基金
山东省泰安市科技发展计划项目(201440774-29B)
