自膨式与球囊扩张支架治疗椎动脉颅内段狭窄患者的临床疗效对比分析

The Clinical Analysis of Self Expanding and Balloon Expandable Stent for Vertebral Artery Intracranial Segment Stenosis

目的探讨自膨式与球囊扩张支架治疗椎动脉颅内段狭窄患者的临床疗效差异。方法选取我院神经内科住院部椎动脉颅内段狭窄患者96例,根据支架置入类型将其分为两组,A组50例和B组46例。A组采用自膨式支架治疗,B组采用球囊扩张支架治疗。比较两组患者临床疗效的差异。结果治疗前,两组患者Mori分型、椎动脉颅内段狭窄率、NIHSS评分比较差异无统计学意义(P>0.05),治疗后,全部患者椎动脉颅内段残余狭窄率均<30%,且椎动脉颅内段狭窄率与NIHSS评分,Mori B、C分型比例明显低于治疗前,比较差异具有统计学意义(P<0.05),其中A组椎动脉颅内段残余狭窄率明高于B组,A组NIHSS评分与围术期并发症发生率明显低于B组,比较差异具有统计学意义(P<0.05)。结论自膨式支架治疗椎动脉颅内段狭窄患者的临床疗效显著,有助于显著改善神经恢复功能与降低围术期并发症发生风险。

Objective To investigate the clinical efficacy difference of self expanding and balloon expandable stent for vertebral artery intracranial segment stenosis. Methods 96 cases of vertebral artery intracranial segment stenosis from neurology inpatient department in our hospital were selected, according to the types of stent implantation,all were divided into two groups, A group（n=50） were given self expanding stent in the treatment, B group（n=46） were given balloon expandable stent in the treatment, the clinical efficacy beetween the two groups were compared. Results Before treatment, Mori type,the ratio of intracranial vertebral artery stenosis, NIHSS score compared between the two groups had no statistically significant differences（P〉0.05）, after treatment,all patients with the ratio of intracranial vertebral artery stenosis was 30%, Mori A type proportion,the ratio of intracranial vertebral artery stenosis and and NIHSS score were significantly higher than pre-therapy, the proportion of Mori B, C type were significantly lower than that pretherapy, the difference had statistical significance（P〈0.05）,in which intracranial vertebral artery stenosis rate of A group was significantly higher than B group,NIHSS score and peri-operative complication rate of A group were significantly lower than that B group, the difference had statistical significance（P〈0.05）. Conclusion The clinical efficacy of self expanding stent in the treatment of patients with vertebral artery intracranial segment stenosis is significant, it is helpful to improve the nerve function recovery and peri-operative complication risk.