汉族和哈萨克族慢性牙周炎的严重程度与IL-6和IL-17相关性分析

The correlation between chronic periodontitis and IL-6 and IL-17 expression in serum and saliva of Kazak and Han subjects

纳入新疆木垒地区慢性牙周炎(CP)患者116例,62例汉族组,54例哈萨克族组。以口腔健康的50例汉族,45例哈萨克族为对照。ELISA检查血液和唾液中IL-6、IL-17水平。血清与唾液IL-6和IL-17水平病例组高于对照组(P<0.05),随CP严重程度而升高(P<0.05),哈萨克族病例高于汉族病例组(P<0.05)。

IL-6 and IL-17 levels in saliva and serum were measured by ELISA in 116 cases of chronic periodontitis（ CP） in Mulei district of Xinjiang,including 62 cases of Han and 54 of Kazak. Health controls included 50 subjects of Han and 45 of Kazak. IL-6 and IL-17 levels in serum and saliva were higher in CP groups than in the controls（ P 〈0. 05）,and correlated with the severity of CP（ P 〈0. 05）,in Kazak CP group were higher than in Han CP group（ P 〈0. 05）.