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不同麻醉方法对胃癌NF-κB因子的作用观察

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摘要 将本院80例胃癌患者纳入研究,随机均分为连续硬膜外阻滞组(E)、全麻复合硬膜外阻滞组(E+G组)和单纯全麻组(G组)。比较三组患者术后2h、术后24h、术后48h静息状态疼痛评分(VAS),以及外周血NF-κB因子浓度的变化。结果术后2h及术后24h三组患者VAS评分无统计学差异(P均>0.05),术后48h三组VAS明显降低(P均<0.05),其中E+G组降低的幅度最明显(P均<0.05),外周血NF-κB因子浓度具有相同的表达趋势。全麻复合硬膜外阻滞可介导NF-κB抑制手术引起的机体应激反应,有助于预后恢复。
作者 石磊 袁玲芳
机构地区 中山市三角医院
出处 《现代诊断与治疗》 CAS 2016年第3期489-491,共3页 Modern Diagnosis and Treatment
基金 项目编号:2015A020130
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参考文献5

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