Lenstar及Pentacam与A超测量白内障患者眼生物参数的比较（英文）

Comparison of the biometric measurements obtained using the Lenstar, Pentacam and ultrasound pachymetry methods in cataract patients

目的:比较光学相干生物测量仪(Lenstar)、三维眼前节分析仪(Pentacam)和A型超声测量仪(A-scan)在白内障患者中测量角膜中央厚度、角膜曲率、前房深度和眼轴长度结果的差异。方法:分别用3种仪器对158例(158眼)白内障患者进行眼部生物测量,比较角膜中央厚度、角膜曲率、前房深度和眼轴长度的结果,采用重复测量的方差分析及Pearson相关分析,一致性比较采用Bland-Altman统计分析法。结果:Lenstar和Pentacam测得的角膜中央厚度分别为536.54±27.90μm和541.46±29.85μm,两者差异有统计学意义(t=-5.439;P<0.001);K值分别为43.87±1.45D和43.86±1.44 D,两者差异无明显统计学意义(t=-0.348,P>0.05)。Pentacam、Lenstar和A超测量的前房深度分别是2.73±0.38mm、2.71±0.38mm和2.85±0.40mm,三者差异均有统计学意义(F=309.94,P<0.001),Pearson相关分析显示三者呈正相关(r=0.989,0.978,and 0.977;P<0.001),但变异系数较小(CV=3.12%)。A超和Lenstar测量的眼轴长度分别是24.28±1.70mm和24.52±1.73mm,两者差异有统计学意义(t=-19.482,P<0.001,r=0.996;P<0.001)。BlandAltman分析显示,对于这几种眼前节参数,三种方法测量的一致性较好。结论:三种仪器测量的结果尽管有一定差异,但Lenstar和Pentacam的生物测量可重复性好,操作简便更易用于白内障患者的检查。

AIM：To compare the central corneal thickness（CCT）,keratometry（K） reading,anterior chamber depth（ACD）,and axial length（AL） measured with Lenstar and Pentacam with those obtained with the ultrasound（US）pachymetry in the cataract patients.METHODS：A total of 158 eyes of 158 patients were examined in this study.The CCT,average K,ACD and AL obtained by Lenstar and /or Pentacam were compared with those obtained from US pachymetry using repeated-measures analysis of variance,Pearson correlation coefficients and Bland-Altm an analyses.RESULTS：The mean CCT obtained using Lenstar and Pentacam were 536.54 ±27.90μm and 541.46 ±29.85μm（t=-5.439;P〈0.001）.The mean Km obtained using Lenstar and Pentacam methods were 43.87±1.45 D and 43.86±1.44 D（t=-0.348,P〈0.05）.The mean ACD measured using the Pentacam,Lenstar,and US pachymetry were 2.73±0.38 mm,2.71 ±0.38 mm,and 2.85±0.40 mm,respectively（F=309.94,P 0.001）,and they were positively correlated（r=0.989,0.978,and 0.977;P〈0.001） and the coefficient of variation was small（3.12%）.The mean AL obtained by US pachymetry and Lenstar were 24.28±1.70 mm and 24.52±1.73 mm,respectively（t=-19.482,P 0.001,r=0.996;P 0.001）.The Bland-Altman analysis showed that the three methods were comparable for CCT,Km,ACD and AL.CONCLUSION：Although there were statistically significant differences,the measurements obtained by the Lenstar and the Pentacam were highly repeatable and the instruments easy to use.