飞秒激光微小切口角膜基质透镜取出术对角膜内皮细胞的影响被引量：2

The influence of small incision lenticule extraction with femtosecond laser on corneal endothelial cells

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摘要目的探讨飞秒激光微小切口角膜基质透镜取出术(small incision lenticule extraction,SMILE)对术后患者角膜内皮细胞的影响。方法自愿接受SMILE且常规术前检查确认为适应证的患者,共100例(200眼),分别于术前和术后1、3、6个月进行角膜内皮检查,观察并统计分析术后角膜内皮细胞密度、变异系数、六角形细胞百分比、平均细胞面积的变化。结果所有患者手术顺利,无术中术后并发症。术后各时间点与手术前角膜内皮细胞密度、变异系数、六角形细胞百分比、平均角膜细胞面积变化均无统计学差异(P>0.05)。结论 SMILE手术对术后0.5年角膜内皮细胞变化无影响,远期是否有影响有待进一步观察。 Objective To evaluate the effect of SMILE（small incision lenticule extraction） on corneal endothelial cells. Methods A total of 100 cases（200 eyes） were enrolled in this study. They underwent routine preoperative examinations and accepted SMILE. Corneal endothelial cell density,coefficient of variation,percentage of hexagonal cells and average cell area were measured and statistically analysed respectively at the preoperation and postoperative 1 month,3 months,6 months. Results There was no complicatins in all the patients after surgery. There were no statistical difference of corneal endothelial cell density,coefficient of variation,percentage of hexagonal cells and average cell area between postoperative 1,3,6 months and preoperation（P 〉0.05）.Conclusion Six monthes after SMILE corneal endothelial cells were not effected,but more longer-term influence is needed to be furture observed.

作者李世洋邢星刘雪雁赵爱红马红利肖建和

机构地区解放军

出处《实用医药杂志》 2016年第3期219-221,共3页 Practical Journal of Medicine & Pharmacy

基金洛阳市科技局基金资助项目(No:1401086A-4)

关键词角膜内皮细胞计数飞秒激光角膜基质透镜取出术 Corneal endothelial cell count Femtosecond laser Small incision lenticule extraction

分类号 R772.7 [医药卫生—眼科]

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参考文献12

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