山东农村居民肠道蠕虫感染及驱虫疗效分析

Prevalence of intestinal helminthes and effect of anthelmintic treatment among rural residents in Shandong province

目的掌握山东省人体肠道蠕虫感染流行现状及全民服药驱虫效果,为采取相应措施提供依据。方法以整群抽样方法对34 384名山东农村居民采用改良加藤厚涂片法(Kato-Katz)和透明胶纸肛拭法检查肠道蠕虫感染情况,在感染率≥20%的重点县市,以阿苯达唑全民服药法控制土源性线虫感染并考核其疗效。结果调查农村居民34 384人,肠道蠕虫总感染率为3.51%,其中蛔虫感染率为0.49%,钩虫为0.1%,鞭虫为2.57%,蛲虫为3.27%,华支睾吸虫为0.01%;农村居民全民化疗人群141.19万,土源性线虫感染率较化疗前大幅下降。结论山东省肠道蠕虫的虫种、感染率、感染度、多虫种感染现象均有大幅下降;阿苯达唑全民化疗降低农村居民土源性线虫感染率效果显著。

Objective To examine the prevalence of intestinal helminthes and the effects mass anthelmintic administration among rural residents in Shandong province and to provide evidences for implementing control measures for the diseases. Methods Totally 34 384 permanent rural residents aged ≥ 3 years were recruited with cluster sampling from34 municipalities,districts or counties for a survey on intestinal helminthes infection with modified Kato-Katz method and cellophane anal swab. Mass administration of albendazol was conducted in the residents living in the counties with an intestinal helminthes infection rate of ≥ 20% and then the treatment outcome was evaluated. Results The overall intestinal helminthes infection rate was 3. 51%（ 1 207 /34 384）,and the infection rates were 2. 57%（ 884 /34 384） for whipw-orm,0. 49%（ 168 /34 384） for roundworm,0. 1%（ 38 /34 384） for hookworm,0. 01%（ 3 /34 384） for Clonorchis sinensis,and 3. 27%（ 165 /5 047） for pinworm among the residents aged 3- 12 years,respectively. After the mass administration of albendazol,the overall infection rate of soil-borne nematodes decreased by 64. 48% among the 1. 41 millions participants in a municipality and a county. Conclusion There are significant decreases in the number of parasites,infection rate and intensity,multiple infection of intestinal helminthes and mass administration of albendazol for the control of soilborne nematodes infection achieved remarkable outcome among the rural residents in Shandong province.