盘锦市2013—2014年呼吸道症候群病原学分析

Respiratory syndrome related pathogens isolated in Panjin municipality,2013- 2014

目的了解辽宁盘锦市发热呼吸道症候群的病原普构成,对临床诊断、治疗与预防提供依据。方法采集2013—2014年盘锦市中心医院呼吸道临床患者标本,运用荧光定量PCR技术进行检测。结果 150份样品中,检出12种病原核酸共76份,检出率为50.7%,多重感染占14.5%(11/76)。流感病毒16例(10.7%),肺炎链球菌13例(8.7%),金黄色葡萄球菌9例(6.0%),腺病毒8例(5.3%),鼻病毒7例(4.7%),肺炎支原体6例(4.0%),副流感病毒6例(4.0%),合胞病毒3例(2.0%),冠状病毒3例(2.0%),流感嗜血杆菌2例(1.3%),偏肺病毒2例(1.2%),肺炎支原体1例(0.7%)。结论构成盘锦地区呼吸道感染病原种类繁多,主要以流感病毒、肺炎链球菌、金黄色葡萄球菌、腺病毒为主,在监测月份中,呼吸道感染均高位流行。

Objective To examine common pathogens of febrile respiratory syndrome in Panjin municipality of Liaoning province and to provide bases for clinical diagnosis,treatment and prevention of the disease. Methods Clinical specimens were collected from outpatients with febrile respiratory syndrome in Panjin Municipal Central Hospital between2013 and 2014. PCR technology was used in pathogen detection. Results Of the 150 specimens,76 were positive for nucleic acids of 12 pathogens,with a detection rate of 50. 7%,and of the pathogen positive specimens,14. 5% were multiple pathogen positive. For the 76 positive specimens,the pathogens included influenza virus（ 16,10. 7%）,Streptococcus pneumoniae（ 13,8. 7%）,Staphylococcus aureus（ 6. 0%）,adenovirus（ 8,5. 3%）,rhinovirus（ 7,4. 7%）,Mycoplasma pneumonia（ 6,4. 0%）,parainfluenza virus（ 6,4. 0%）,synthetic syncytial virus（ 3,2. 0%）,coronavirus（ 3,2. 0%）,Haemophilus influenzae（ 2,1. 3%）,partial lung virus（ 2,1. 2%）,and Mycoplasma pneumoniae（ 1,0. 7%）. Conclusion There are multiple pathogens for respiratory tract infections in Panjin municipality and the main pathogens are influenza virus,Streptococcus pneumoniae,Staphylococcus aureus,and adenovirus.