双补一泻针法治疗类风湿关节炎风寒湿阻证临床研究

Clinical Research of Applying Acupuncture Method of Double Reinforcing and Single Reducing in the Treatment of Rheumatoid Arthritis

目的:观察"双补一泻"法治疗类风湿关节炎风寒湿阻证的临床疗效。方法:通过三个分中心按美国风湿病协会(ACR)和欧洲抗风湿病联盟(EULAR)2009年的RA分类标准和中医病证诊断疗效标准中类风湿关节炎风寒湿阻证的诊断标准选择类风湿关节炎患者108例,按随机数字表分为2组治疗,即试验组及对照组,试验组为"双补一泻"法配合西药,对照组为单纯西药组,评定治疗前、治疗后4周、8周的血常规、肝肾功、血沉、C反应蛋白、类风湿因子、关节触痛数、关节肿胀数,DAS28评分并评判其中医证候疗效。结果:治疗组在血沉、CRP、关节触痛数、关节肿胀数,DAS28方面优于对照组(P<0.05)。结论:"双补一泻"法治疗对类风湿关节炎患者的关节症状及炎症控制都有较好的效果。

Objective： To observe clinical effect of RA patients（ wind-cold-damp syndrome） which treated by tonifying liver kidney and inducing cold and damp. Choosing 108 RA patients（ wind-cold-damp syndrome） according to RA classification standard making by ACR and EULAR,and TCM effect standard of etiological syndrome. 108 cases were randomly divided into2 groups,treatment group and controlled group. DMARDs were administrated to both of groups,- tonifying liver and kidney and inducing cold-damp. was used in the treatment group. The clinical manifestation,lab exam,DAS28 were observed and analyzed before treatment and the 4and 8weeks after treatment. Results： The treatment group had significant difference in clinical manifestation,lab exam,DAS28 and TCM effect compared with the controlled group（ P0. 05）. Conclusions： The method of tonifying liver and kidney and inducing cold-damp is effective in relieving clinical symptom and improve lab exam.