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减低剂量TA化疗方案治疗高龄急性髓系白血病效果观察 被引量:2

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摘要 目的探讨减低剂量TA化疗方案(吡柔比星+阿糖胞苷)治疗高龄急性髓系白血病(AML)的效果。方法将39例高龄AML患者随机分为观察组19例和对照组20例,分别采用减低剂量、标准剂量的TA方案化疗,化疗至少2个周期。结果观察组和对照组化疗后总有效率分别为52.6%、65.0%,P>0.05;与对照组比较,观察组血小板下降、白细胞减少、恶心呕吐及感染的程度及发生率均降低(P均<0.05);观察组中位总生存时间为6.1个月,对照组为5.0个月,P<0.05。结论减低剂量TA化疗方案治疗高龄AML效果较好,不良反应轻,可延长患者的生存期。
作者 朱斌 丁志勇
出处 《山东医药》 CAS 北大核心 2016年第10期56-57,共2页 Shandong Medical Journal
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