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斯钙素1在肾脏中的研究进展 被引量:1

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摘要 斯钙素(Stanniocalcin,STC)是一种于硬骨鱼体内负责调节钙磷代谢的糖蛋白激素,后于哺乳动物及人体内均发现与其同源的斯钙素蛋白存在.其中斯钙素1(STC1)除钙磷代谢外,在抗炎、抗氧化应激、生长调节、心血管系统及肿瘤发展方面均有显著作用.哺乳动物肾脏是斯钙素1高表达的器官,且肾脏损伤常表现为氧化应激损害,基于以上,斯钙素在肾脏疾病方面的作用逐渐引起科学界的关注.本文以斯钙素为中心,围绕其分子代谢特征、在肾脏的表达调控及在肾脏疾病中的作用作一综述.了解斯钙素在肾脏方面的研究进展、发现研究空缺,为斯钙素在肾脏中的进一步研究提供帮助.
作者 吴艳 廖晓辉
出处 《国际泌尿系统杂志》 2016年第2期314-318,共5页 International Journal of Urology and Nephrology
关键词 激素类
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参考文献28

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