某医院新生儿科医院感染目标性监测结果分析

Analysis on objective monitoring results of nosocomial infection of neonate departmene in a hospital

目的了解医院新生儿科住院患儿医院感染情况,为有效控制新生儿医院感染提供参考。方法采用前瞻性研究方法,对某医院新生儿科住院所有新生儿医院感染状况进行目标性监测,检测病原菌并进行耐药性分析。结果共监测住院新生儿3 963例,监测到医院感染新生儿158例、182例次,医院感染率为3.99%、例次感染率为4.59%。新生儿医院感染以下呼吸道感染和血液相关感染占主导,其次是上呼吸道感染、口腔感染和眼感染。新生儿出生时胎龄越小、出生体重越轻,医院感染率越高。新生儿感染病原菌居前5位的分别是大肠埃希菌、葡萄球菌、鲍曼不动杆菌、肺炎克雷伯菌和真菌。临床分离的革兰阴性菌对头孢类抗菌药物耐药率均超过50%。结论住院新生儿出生时胎龄越小、体重越轻,医院感染发生率越高,通过目标监测可有针对性地采取防控措施。

Objective To understand the hospital infection in the hospital,and provide reference for the effective control of neonatal nosocomial infection. Methods Using the prospective study method,the objective monitoring and drug resistance analysis of nosocomial infection in all neonates were carried out in a hospital. Results 3 963 cases of neonatal were monitored,158 person and 182 cases had nosocomial infection,hospital infection rate was 3. 99%,case infection rate was4. 59%. Infection of respiratory tract and blood associated infection were the main infection in newborn hospital,followed by upper respiratory tract infection,oral infection and eye infection. The smaller the gestational age,the lighter the birth weight,the higher the hospital infection rate. Neonatal infection pathogens in the top 5 were Escherichia coli,Staphylococcus,Bauman Acinetobacter,Klebsiella pneumoniae Lei Bojun and fungi. Clinical isolated Gram- negative bacteria were resistant to more than 50% of the antimicrobial agents. Conclusion The smaller the gestational age,the smaller the weight,the higher the incidence rate of nosocomial infection,therefore,it can be targeted to take prevention and control measures.