百蕊草化学成分分离

Isolation of Chemical Components from Thesium chinense

目的：研究百蕊草的化学成分。方法：对百蕊草95%乙醇提取物采用各种柱色谱方法分离纯化,通过理化常数测定和光谱分析鉴定化合物结构。结果：从百蕊草中分离纯化了10个化合物,分别鉴定为木犀草素-7-O-葡萄糖苷（1）,芹菜素-7-O-葡萄糖苷（2）,芦丁（3）,芹菜素-8-C-α-L-阿拉伯糖苷（4）,高车前苷（5）,大蓟苷（6）,蒙花苷（7）,芹菜素-7-O-β-D-葡萄糖醛酸苷（8）,柯伊利素-7-O-β-D-葡萄糖醛酸苷（9）,金圣草黄素（10）。结论：化合物10为首次从百蕊草属植物中分离得到,化合物4-9为首次从檀香科植物中分离得到。

Objective： To investigate the chemical components of Thesium chinense. Method： Various column chromatography methods were used to isolate and purify the compounds from 95% ethanol extracts of T. chinense,and their structures were identified by physico-chemical and spectral analysis. Result： Ten compounds were isolated from T. chinense and identified as luteolin-7-O-glucoside（ 1）,apigenin-7-O-glucoside（ 2）,rutin（ 3）,apigenin-8-C-α-L-arabinopyranoside（ 4）,homoplantaginin（ 5）,pectolinarin（ 6）,linarin（ 7）, apigenin-7-O-β-D-glucopyranuronide（ 8）, chrysoeriol 7-O-glucuronide（ 9） and chrysoeriol（ 10）.Conclusion： Compound 10 was isolated from the genus Thesium for the first time and compounds 4-9 were isolated from the family Santalaceae for the first time.