抗肿瘤坏死因子疗法在炎症性肠病中的应用

Application of Anti-tumor Necrosis Factor Therapy in Inflammatory Bowel Disease

目前,抗肿瘤坏死因子疗法在炎症性肠病的治疗中发挥着重要的作用。在炎症性肠病中使用抗肿瘤坏死因子抗体可能是至关重要的,以实现最终目的即肠道黏膜愈合。在疾病的早期阶段,特别是在克罗恩病患者中,建议使用抗肿瘤坏死因子抗体。但由于其成本、副作用、药物浓度监测等问题,使抗肿瘤坏死因子抗体备受争议。本文就最新相关数据来探讨抗肿瘤坏死因子抗体在炎症性肠病中的应用。

At present,the anti-tumor necrosis factor therapy plays an important role in the treatment of inflammatory bowel disease.Using of anti-tumor necrosis factor antibody in inflammatory bowel disease in order to achieve the ultimate objective of intestinal mucosal healing may be crucial. In the early stages of the disease,especially in Crohn＇s disease,it is recommended to use anti-tumor necrosis factor antibody. However,due to its cost,side effects,drug concentration monitoring and other issues,using of anti-tumor necrosis factor antibody is controversial. In this paper,the application of anti-tumor necrosis factor antibody in inflammatory bowel disease is explored with the latest data.