非ST段抬高心肌梗死患者血清胱抑素C水平的影响因素分析

Infl uence factors of serum cystatin C level in patients with non-ST-segment elevation myocardial infarction

目的探讨非ST段抬高心肌梗死(NSTEMI)患者血清胱抑素C(Cys-C)水平的影响因素。方法纳入74例NSTEMI患者,比较治疗前后血清Cys-C水平,关联分析Cys-C水平与一般资料和临床特征之间的关系。结果治疗后第10和30 d血清Cys-C水平显著升高(P均<0.05);饮酒史和治疗方式与治疗后血清Cys-C水平变化相关(P均<0.05),无饮酒史和选择介入治疗的患者,其治疗后血清Cys-C水平更高。结论血清Cys-C水平在NSTEMI发生时异常升高,经治疗后短期内继续升高,其变化受到饮酒史和治疗方式的影响。

【Objective】To explore the infl uence factors of serum cystatin C（Cys-C） level in patients with non-ST-segment elevation myocardial infarction（NSTEMI）.【Methods】Seventy-four cases with NSTEMI were included, serum Cys-C levels before and after treatment were compared, and the correlations between Cys-C level with general information and clinical characteristics of patients were analyzed.【Results】Serum Cys-C levels were signifi cantly increased on the 10 th and 30 th day after treatment（P〈0.05）; drinking history and methods of treatment were associated with serum Cys-C level（both P 0.05）, patients without drinking history and treated by intervention had higher serum Cys-C level after treatment.【Conclusion】Serum Cys-C level is increased abnormally when NSTEMI occurs, and sequentially increased within a short-term period after treatment. The changes of serum Cys-C level is easily affected by drinking history and methods of treatment.