摘要
[目的]观察黄芪桂枝五物汤联合甲钴胺治疗糖尿病性周围神经病疗效。[方法]使用随机平行对照方法,将54例住院及门诊患者按抛硬币法简单随机分为两组。对照组27例甲钴胺,0.5mg/次,3次/d。治疗组27例黄芪桂枝五物汤(桂枝、当归、丹参、茯苓、赤芍各15g,红花、地龙各12g,白芍10g,黄芪50g,鸡血藤30g,生地黄20g,生姜2片,甘草6g),1剂/d,水煎400mL,早晚口服;西药治疗同对照组。连续治疗21d为1疗程。观测临床症状、神经传导速度、不良反应。治疗1疗程,判定疗效。[结果]治疗组显效18例,有效7例,无效2例,总有效率92.59%。对照组显效10例,有效9例,无效8例,总有效率70.37%。治疗组疗效优于对照组(P<0.05)。神经感觉传导速度两组均有改善(P<0.05),治疗组改善优于对照组(P<0.05)。[结论]黄芪桂枝五物汤联合甲钴胺治疗糖尿病性周围神经病疗效满意,无严重不良反应,值得推广。
[Objective]To observe the effect of Guizhi decoction of five ingredients combined with methylcobalamin treatment of diabetic peripheral neuropathy.[Methods]Randomized parallel controlled method,54 cases of inpatient and outpatient simply by flipping a coin law randomly divided into two groups.27 cases in the control group mecobalamin,0.5mg/time,3 times/d.The treatment group 27 cases HuangQiGuiZhi soup(Guizhi,Danggui,Danshen,Fuling,Chishao 15 g,Honghua,Dilong 12 g,Baishao 10 g,Huangqi 50 g,Jixueteng 30g,Shengdihaung 20 g,Shengjiang 2,Gancao 6g),l ji/d,decoction 400 mL,sooner or later,oral,200mL/second;western medicine with the control group.21 d for a course of continuous treatment.Observation of clinical symptoms,nerve conduction velocity,adverse reactions.One course of treatment,to determine efficacy.[Results]The treatment group 18 cases.effective in 7 cases,2 cases,the total efficiency of 92.59%.The control group 10 cases markedly effective in 9 cases,8 cases,the total efficiency 70.37%.Treatment group than the control group(P〈0.05).Sensory nerve conduction velocity improved in both groups(P〈0.05),treatment group was better than that in the control group(P〈0.05).[Conclusion]HuangQiGuiZhi soup joint mecobalamin neurological complications of diabetes results were satisfactory,no serious adverse reactions,it is worth promoting.
出处
《实用中医内科杂志》
2016年第2期61-63,共3页
Journal of Practical Traditional Chinese Internal Medicine