女性糖调节受损患者降低膳食血糖负荷对血糖的影响

Decrease in glycemic load benefits glycemic control in patients with impaired glucose regulation

目的:研究女性糖调节受损(IGR)患者膳食血糖负荷(GL)与血糖变化之间的关系。方法:筛查参与我院2型糖尿病流行病学调查的广州社区40～79岁居民,纳入120例女性IGR患者作为研究对象,随访12个月。膳食调查采用连续3 d 24 h膳食回顾法,并测定研究对象在研究起始和结束时的血糖水平,分析不同膳食GI、GL与血糖变化的关系。结果:99例完成12个月的研究。按照GL变化百分比(ΔGL)分为Ⅰ组(ΔGL<-30%)、Ⅱ组(ΔGL-30%～-10%)和Ⅲ组(ΔGL≥-10%)。Ⅰ组及Ⅱ组Hb A1c降低率均大于Ⅲ组(P<0.05)。结论:女性IGR患者膳食GL降低10%或以上有利于改善糖化血红蛋白水平。

Objective To investigate the effect of dietary glycemic load（GL） on the blood glucose level in women with impaired glucose regulation. Methods A total of 120 women with impaired glucose regulation aged from 40 to 79 were enrolled from Guangzhou community to participate in the epidemiological survey on diabetes mellitus, and were followed up for 12 months. Continues 24-hour dietary review of 3 days were completed before and after intervention. The dietary GI, GL and the changes of blood glucose level during the 12-month follow-up were analyzed. Results Ninety-nine subjects completed the 12-month follow-up. According to the GL change percentage（ΔGL）, all of the subjects were divided into three groups, including group Ⅰ（ΔGL -30%）、group Ⅱ（ΔGL-30%～-10%） and group Ⅲ（ΔGL≥-10%）. The reductions of Hb A1 c in group Ⅰ and groupⅡ were greater than that in group Ⅲ（P 〈0.05）. Conclusion To lowering dietary GL at 10% or more should be conductive to reduce Hb A1 Cof women with inpaired glucose regulation.