急性ST段抬高心肌梗死介入治疗后体温升高对左室功能的影响

Effects of Elevated Temperature on Left Ventricular Function in Patients with Acute ST Segment Elevation Myocardial Infarction after PCI

目的:探讨急性心肌梗死(AMI)后体温升高对左室功能的影响。方法:选择2011年1月至2013年3月因急性ST段抬高心肌梗死行急诊PCI治疗成功的患者176例,测量腋下体温,每6h1次,连续测量1周。按体温峰值分为体温正常组(A组,体温<37.3℃)和体温升高组(B组体温≥37.3℃),比较两组间临床特征、心肌酶(肌酸激酶同工酶CK-MB)、炎症指标及心功能的差异。结果:A组心肌酶、hs-CRP水平、白细胞计数明显较高(P<0.05),而左室射血分数低于B组(P<0.05)。结论:AMI再灌注后发热仍然与坏死面积大小及心功能受损有关,提示预后不良。

[ABSTRACT]Objective:To investigate the effect of elevated temperature on left ventricular function in patients with acute myocardial infarction(AMI). Methods:176 patients with acute ST segment elevation myocardial infarction treated by PCI were selected from January 2011 to March 2013, 1/6h, 1 week, measured under the armpit temperature. According to the temperature peak points with elevated temperature normal group (group A, temperature<37.3℃) and body temperature group (group B temperature≥37.3℃), the differences were compared between the two groups clinical features, myocardial enzyme (creatine kinase isoenzyme,CK-MB), markers of inlfammation and cardiac function. Results:The levels of myocardial enzymes, hs-CRP and P<0.05 were signiifcantly higher in A group than in B group (P<0.05). Conclusion:Fever is still associated with the size of necrotic area and impaired cardiac function in AMI after reperfusion, suggesting a poor prognosis.