结肠癌分期对实施完整结肠系膜切除的应用价值和远期疗效

Application Value and Long-term Efficacy of Colon Cancer Staging for Patients with Complete Resection of the Mesocolon

目的探讨结肠癌的分期对实施完整结肠系膜切除的应用价值及远期疗效。方法采用结肠癌分期标准Dukes分期方法进行术前分期,Dukes A期20例、B期35例、C期28例、D期17例。所有患者都实施完整结肠系膜切除术,制定10年的远期疗效观察目标。结果淋巴结清扫量:Dukes A期(21.25±4.02)枚,B期(20.56±3.89)枚,C期(13.32±2.88)枚,D期(12.23±2.45)枚,Dukes A、B期数量明显多于C、D期数量;平均出血量、并发症发病率:Dukes A期<B期<C期<D期,组间差异具有统计学意义;手术时间、术后的排气时间、住院时间,4期患者比较,差异无统计学意义;1年总体复发率和生存率4组间无统计学差异,5年及10年复发率和生存率4组间具有统计学差异。结论Dukes分期对评估完整结肠系膜切除的可行性及远期疗效具有一定的临床指导价值。

Objective To explore the application value and long-term efficacy of colon cancer staging for patients with complete resection of the mesocolon. Methods Dukes stages of colon cancer staging received standard methods of preoperative staging, Dukes A was 20 cases, Dukes B was 35 cases, Dukes C was 28 cases, Dukes D was 17 cases. All patients received com- plete resection of mesocolon, and 10 years long-term efficacy of observation target were determined. Results The number of lymph node dissection,Dukes A was 21.25±4.02 medals, B was 20.56±3.89 medals, C was 13.32 ± 2.88 medals, D was 12.23 ± 2.45 medals. Dukes A, B were significantly more than those of the Dukes C, D;The average blood loss, complication rate： Dukes A 〈 B 〈 C 〈 D, there had statistically significant difference ;operative time,postoperative exhaust time, hospital stay of the 4 groups had no statistically significant difference ; 1-year recurrence rates and survival rates of the 4 groups had no statistically significant difference, and 5-and 10-year recurrence rates and survival rates of the 4 groups had statistically significant difference. Conclusion Dukes has some clinical value in guiding the evaluation of feasibility and long-term efficacy of complete resection of mesocolon.