宫颈冷刀锥形切除和LEEP治疗CINⅡ级的预后观察

Observation of Prognosis of Cervical Cold Knife Cone Excision and LEEP for CIN Ⅱ

目的观察分析宫颈冷刀锥形切除和宫颈环形电切术(LEEP)治疗CINⅡ级的预后及疗效情况。方法将148例CINⅡ级患者随机分为两组,LEEF组患者74例采用LEEF手术治疗;CKC组患者74例采用CKC手术治疗。统计两组患者术中出血量、手术时间、住院时间和住院费用。观察两组患者随访情况、并发症情况以及术后疗效情况。结果 LEEF组患者的出血量、手术时间、住院时间和住院费用均明显少于CKC组患者(P<0.05)。术后宫颈修复光滑例数,TCT检查、阴道镜检查和HPV检查阴性例数,两组比较无明显差异(P>0.05)。LEEF组患者术后发生宫颈管狭窄和术后出血例数明显少于CKC组患者(P<0.05)。两组患者的术后疗效比较差异不明显(P<0.05)。结论 LEEF治疗CINⅡ级操作更简便,治疗效果更好,并发症发生率低,安全性高。

Objective To investigate the prognosis and efficacy of cervical cold knife cone excision and loop electrosurgical excision procedure （LEEP） for CIN Ⅱ. Methods 148 cases of CIN II were randomly divided into 2 groups. LEEF group （74 patients） were treated by LEEF surgery, and CKC group （74 patients） were treated by CKC surgery. Blood loss, operative time,length of stay and hospital costs of the 2 groups were counted. Follow-up results, complications and postoperative effects of the 2 groups were analyzed. Results Blood loss, operative time,length of stay and hospital costs of LEEP group were significantly less than those of CKC group patients （P 〈 0.05 ）. The number of postoperative cervical smooth repair and the negative results of TCT examination, colposcopy and HPV examination of the 2 groups had no significant difference （P 〉 0.05 ）. The number of cervical stenosis and postoperative bleeding of LEEF group were less than those of CKC group （P 〈 0.05）. Postoperative efficacy of the 2 groups had no significant difference （P 〉0. 05）. Conclusion LEEF for CIN Ⅱ is easier to operate and has better therapeutic effects, and complication rate is low and the safety is high.