输血4项检测及临床意义分析

Analysis of results and significance of detecting four blood-borne disease

目的:分析住院患者4项血液传播性疾病指标的检测结果,探讨感染现状及检测意义。方法:用化学发光法(CLIA)检测HBsAg、抗-TP、抗-HIV和抗-HCV 4项指标,统计分析结果。结果:2010-2014年,HBsAg、抗-TP、抗-HIV和抗-HCV的平均阳性率分别为9.82%、6.85%、0.90%和0.40%,各年比较差异有统计学意义(P<0.05)。4项血液传播性疾病在各临床科室广泛存在。结论:医院血液传播性疾病感染率较高,尤其TP、HIV的传播不容忽视;加强住院患者血液传播性疾病标志物检测,无论对患者(可发现无症状感染)、医院(控制交叉感染及职业暴露感染)、还是卫生行政部门(制定预防控制策略)均有重要意义。

Objective：To analyze the test results of four blood-borne disease index in hospitalized patients,and investigate the infection situation and significance of detecting.Method：HBsAg,anti-TP,anti-HIV and anti-HCV were tested by CLIA,and results were analyzed.Result：From 2010 to 2014,the average positive rates were respectively 9.82%,6.85%,0.90% and 0.40%in HBsAg,anti-TP,anti-HIV and anti-HCV.The difference was statistically significant.Four blood-borne diseases existed widely in clinical departments.Conclusion：The infection rates of blood transmitted diseases were comparatively high in hospital,especially the spread of TP and HIV which could not be ignored.Strengthening four markers detection in inpatients,no matter for the patient（asymptomatic infection can be found）,the hospital（infections of cross and occupation exposure can be controlled）,and the administrative department of public health（prevention and control strategy are formulated）,its significance may be very important.