相干光断层扫描诊断息肉样脉络膜血管病变的研究进展

Using optical coherence tomography to diagnose polypoidal choroidal vasculopathy

息肉样脉络膜血管病变（polypoidal choroidal vasculopathy,PCV）表现为眼底后极部脉络膜异常分支血管网末端局限性膨隆,呈息肉状改变,伴复发性出血,并有浆液性或出血性色素上皮脱离.自发现以来,吲哚青绿血管造影（indocyanine green angiography,ICGA）被认为是诊断PCV的金标准.随着相干光断层扫描（optical coherence tomography,OCT）成像技术的不断发展,从时域-OCT中特征性的“双层征”到在谱域-OCT中可清晰呈现的异常血管网和息肉状改变,再到穿透性更强的OCT血管造影技术中扩张的脉络膜血管和息肉状结构反射信号的改变,逐步为PCV的非侵入性诊断提供更多可靠依据.

Polypoidal choroidal vasculopathy （PCV） is recently known as a fundus disease,which is characterised as a peculiar form of choroidal vascular abnormality associated with hemorrhagic or serous detachment of pigmented epithelium in the macula.Indocyanine green angiography（ICGA） is seen as the gold standard of diagnosing PCV.With the development of optical coherence tomography （OCT）,from the timedomain-OCT characteristics of double-layer sign to a change in spectral-domain-OCT clearly presenting abnormal vascular network （BYN） and polyps,and then to OCT angiography which can presents the expansion of the choroidal vascular and polypoidal structure＇s reflected signal changes,this non-invasive diagnosis method provides a more and moer reliable way in diagnosing PCV.