分子生物技术在我国生药学领域的应用历程与发展现状分析

Application of molecular biotechnology in Pharmacognosy

研究通过对《中国知网》收录相关论文的定性与定量分析,梳理并探讨了分子生物技术在我国生药研究领域中的应用历程与发展现状,结果表明:分子生物技术的引入是生药学现代发展的实际需求;分子生物技术在生药研究中已形成稳定的应用领域和研究方向,主要涵盖中药分子鉴定、药用植物分子系统学、药用资源遗传多样性及保护、次生代谢产物的生物合成与调控、道地药材的分子机制研究,以及药用植物的组织培养与育种等7个方面;知识产出具有可持续性,并取得标志性研究成果;独立的知识体系已基本形成,显示出良好的发展潜力。

Using the methods of informetrics analysis,articles retrieved from the database of CNKI were statistically analyzed on development course and knowledge system,so as to reflect the overall situation of pharmacognostical studies by molecular biotechnology.The result shows that the research on pharmacognosy by molecular biotechnology is an inter-disciplinary research area,the major research fields can be divided into 7 categories,including molecular identification of Chinese medicinal materials,molecular systematics and genetic diversity analysis of Chinese medicinal materials,biosynthesis and bioregulation of secondary metabolites in medicinal plants,molecular mechanism and genetic basis of Dao-di Herbs,and tissue culture and molecular breeding in medicinal plants. The research on pharmacognosy by molecular have achieved remarkable progress in recent 20 years,and have broad development prospects.