羊绒纤维的胶原蛋白接枝改性

Grafting modification of cashmere fiber with Collagen

羊绒纤维通过交联剂(戊二醛和异佛尔酮二异氰酸)的架桥作用实现胶原蛋白在其表面的接枝改性。考察接枝过程中反应的时间、温度以及交联剂用量等工艺参数对接枝增重的影响。采用傅里叶变换红外光谱对改性前后羊绒表面化学成分变化进行分析,并对改性前后羊绒纤维的强力、上染百分率、白度、伤口愈合性及抗菌能力进行测试。结果表明:交联剂与羊绒本体及胶原蛋白发生了开环反应,改性后羊毛强度和上染百分率均得到提高,其白度值基本不受影响。伤口愈合性和抗菌结果证明羊绒表面接枝胶原蛋白后具有优异的生物活性。

A modification of cashmere fiber was achieved by the grafting of collagen using aziridine crosslinker（ glutaraldehyde and isophorone diisocyanate）. In the process of grafting,the influence of process parameters（ reaction time, temperature and the amount of crosslinker and biological macromolecules） on graft weight gain was investigated. Surface chemical compositions cashmere fiber are analyzed by Fourier transform infrared spectroscopy,and strength,dye uptake,whiteness,antibacterial behavior and wound healing rate of before and after modification cashmere fiber were tested. The results showed that： infrared spectral features indicated that ring-opening reaction occurred between crosslinker and the cashmere body as well as collagen. After the modification,cashmere strength and its dye uptake were all improved, but its whiteness value was not affected. The results of wound healing and antibacterial confirmed that the cashmere grafted by collagen had excellent biological activity.