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妊娠期代谢性疾病对妊娠结局的影响 被引量:11

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摘要 目的探讨妊娠期代谢性疾病—临床甲状腺功能减退(subclinical hypothyroidism,SCH)、妊娠期糖尿病(gestational diabetes mellitus,GDM)对妊娠结局的影响。方法选择接受甲状腺功能检测及75 g糖耐量检查的建册并分娩的孕妇,依据询问病史、体格检查及检验结果将其分为A组(SCH不合并GDM组)201例,B组(GDM不合并SCH组)272例,C组(SCH+GDM组)84例及D组(正常对照组)1 909例,回顾分析4组患者妊娠并发症(子痫前期、胎盘早剥、胎膜早破、剖宫产率、产后出血)发生率及围产儿结局。结果 C组子痫前期、剖宫产、早产及新生儿窒息发生率均高于其他组,差异有统计学意义(P<0.05);B组子痫前期、剖宫产发生率高于对照组,差异有统计学意义(P<0.05);A组妊娠期并发症及不良妊娠结局与对照组比较,差异无统计学意义(P>0.05)。结论妊娠期代谢性疾病对妊娠结局有不良影响,临床工作中应重视孕期对代谢性疾病的筛查,从而改善妊娠结局。
出处 《河北医药》 CAS 2016年第7期1072-1073,共2页 Hebei Medical Journal
基金 邢台市科学技术研究与发展指导计划项目(编号:2015ZC085)
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  • 1李玉姝 单忠艳 滕卫平 等.甲状腺自身抗体TPOAb和TGAb正常值的研究意义[J].中华检验杂志,2006,29:780-783.
  • 2Morreale de Escobar G,Obregon MJ,Escobar del Rey F.Role of thyroid hormone during early brain development.Eur J Endocrinol,2004,151 (Suppl 3):U25-U37.
  • 3Gyamfi C,Wapner RJ,D' Alton ME.Thyroid dysfunction in pregnancy:the basic science and clinical evidence surrounding the controversy in management.Obstet Gynecol,2009,113:702-707.
  • 4Abalovich M,Amino N,Barbour LA,et al.Management of thyroid dysfunction during pregnancy and postpartum:An Endocrine Society Clinical Practice Guideline.J Clin Endocrinol Metab,2007,92:S1-S47.
  • 5Baloch Z,Carayon P,Conte-Devolx B,et al.Laboratory medicine practice guidelines:laboratory support for the diagnosis and monitoring of thyroid disease.Thyroid,2003,13:3-126.
  • 6Haddow JE,Palomaki GE,Allan WC,et al.Maternal thyroid deficiency during pregnancy and subsequent neuropsychological development of the child.N Engl J Med,1999,341:549-555.
  • 7Klein RZ,Mitchell ML.Maternal hypothyroidism and cognitive development of the offspring.Curr Opin Pediatr,2002,14:443-446.
  • 8Surks MI,Ortiz E,Daniels GH,et al.Subclinical thyroid disease:scientific review and guidelines for diagnosis and management.JAMA,2004,291:228-238.
  • 9de Escobar GM,Ares S,Berbel P,et al.The changing role of maternal thyroid hormone in fetal brain development.Semin Perinatol,2008,32:380-386.
  • 10Pop VJ,de Vries E,van Baar AL,et al.Maternal thyroid peroxidase antibodies during pregnancy:a marker of impaired child development? J Clin Endocrinol Metab,1995,80:3561-3566.

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