不同压力滴定技术对重度睡眠呼吸暂停患者自我管理水平的影响

Influence of different methods of continuous positive airway pressure titration on self-management of severe obstructive sleep apnea hypopnea syndrome

目的探讨不同压力滴定技术对重度睡眠呼吸暂停患者自我管理水平的影响。方法 78例重度阻塞性睡眠呼吸暂停低通气综合征患者,随机分为观察组和对照组各39例,观察组无创通气治疗使用手工压力滴定技术,对照组使用自动压力滴定技术。治疗前及治疗后6个月进行自我管理行为问卷和Calgary生活质量指数量表(sleep apnea quality of life index,SAQLI)评分,并进行2组间比较。结果观察组和对照组治疗前自我管理行为问卷评分[(70.55±8.59)、(69.47±9.87)分]和SAQLI评分[(3.80±0.19)、(3.80±0.24)分]比较差异无统计学意义(P>0.05);治疗6个月后,观察组自我管理行为问卷评分、SAQLI评分分别为76.90±6.50、4.83±0.18,对照组分别为70.55±8.59、4.22±0.26,均较治疗前提高(P<0.05),且观察组高于对照组(P<0.01)。结论无创通气治疗前采用手工压力滴定技术,可提高重度阻塞性睡眠呼吸暂停患者自我管理水平。

Objective To explore the influence of different methods of continuous positive airway pressure titration on self-management of severe obstructive sleep apnea hypopnea syndrome（OSAHS）.Methods Seventy-eight severe OSAHS patients were divided into experimental group and control group,with 39 patients in each group.Experimental group received standards laboratory manual pressure titration,and control group received automatic pressure titration.Both two groups filled in sleep apnea quality of life index（SAQLI）scale and self-management scale,and were compared before and after 6-month treatment.Results There were no significant differences in SAQLI scales（70.55±8.59,69.47±9.87）and self-management scale scores（3.80±0.19,3.80±0.24）between two groups before treatment（P〉0.05）.After 6-month treatment,SAQLI and self-management scores were 76.90±6.50 and 4.83±0.18 in experimental group,significantly higher than those in control group（70.55±8.59,4.22±0.26）（P〈0.01）,both of which were significantly higher than those before treatment（P〈0.05）.Conclusion Standard laboratory manual pressure titration before continuous positive airway pressure treatment could significantly improve the self-management of severe OSAHS patients.