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中性粒细胞胞外诱捕网在系统性红斑狼疮发病机制中的作用 被引量:2

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摘要 系统性红斑狼疮(SLE)是一种具有多种临床表现的复杂的多基因疾病,对自身抗原耐受的降低及多种自身免疫性抗体的产生是它最基本的特征。在过去的几十年内,人们主要关注适应性免疫特别是调节性T细胞、B细胞的异常,以及基因、激素水平、环境等因素在SLE的发病过程中所起的作用。但SLE的确切机制仍未能得到明确阐述。
出处 《中国药物与临床》 CAS 2016年第3期350-352,共3页 Chinese Remedies & Clinics
基金 山西省科技厅攻关项目(20140313012-4)
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参考文献28

  • 1Crispín JC,Kyttaris VC,Terhorst C,et al.T cells as therapeutic targets in SLE[J].Nat Rev Rheumatol,2010,6:317-325.
  • 2Dorner T,Jacobi AM,Lee J,et al.Abnormalities of B cell subsets in patients with systemic lupus erythematosus[J].J Immunol Methods,2011,363:187-197.
  • 3Crispín JC,Liossis SN,Kis-Toth K,et al.Pathogenesis of human systemic lupus erythematosus:recent advances[J].Trends Mol Med,2010,16:47-57.
  • 4Brinkmann V,Reichard U,Goosmann C,et al.Neutrophil extracellular traps kill bacteria[J].Science,2004,303:1532-1535.
  • 5Fuehs TA,Abed U,Goosmann C,et al.Novel cell death program leads to neutrophil extracellular traps[J].J Cell Biol,2007,176:231-241.
  • 6Clark SR,Ma AC,Tavener SA,et al.Platelet TLR4 activates neutrophil extracellular traps to ensnare bacteria in septic blood[J].Nat Med,2007,13:463-469.
  • 7Gupta AK,Joshi MB,Philippova M,et al.Activated endothelial cells induce neutrophil extracellular traps and are susceptible to NETosis-mediated cell death[J].FEBS Lett,2010,584:3193-3197.
  • 8Lande R,Ganguly D,Facchinetti V,et al.Neutrophils activate plasmacytoid dendritic cells by releasing self-DNA-peptide complexes in systemic lupus erythematosus[J].Sci Transl Med,2011,3:73ra19.
  • 9Garcia-Romo GS,Caielli S,Vega B,et al.Netting neutrophils are major inducers of typeⅠIFN production in pediatric systemic lupus erythematosus[J].Sci Transl Med,2011,3:73ra20.
  • 10Fuchs TA,Brill A,Duerschmied D,et al.Extracellular DNA traps promote thrombosis[J].Proc Natl Acad Sci USA,2010,107:15880-15885.

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