前列腺动脉栓塞术治疗良性前列腺增生

Prostatic artery embolization in treatment of benign prostatic hyperplasia

目的评价前列腺动脉栓塞术(PAE)治疗良性前列腺增生(BPH)的可行性、有效性。方法对7例BPH患者行PAE,术后1、6个月复查并收集临床结果,观察比较手术前后国际前列腺症状评分(IPSS)、生活质量评分(QOL)、前列腺体积(PV)、最大尿流率(Q_(max))、剩余尿(RU)的变化。结果 7例患者共完成12支较大前列腺动脉(PA)的栓塞治疗,其中膀胱下动脉发出7支,闭孔动脉2支,阴部内动脉2支,臀下动脉1支。单侧栓塞2例,双侧栓塞5例。与术前比较,术后6个月IPSS显著改善[平均提高(24.00±3.90)分],QOL改善[平均降低(4.00±1.40)分],Q_(max)显著改善[平均改善(8.45±1.90)ml/s],PV显著缩小[平均减少(42.86±21.20)ml],RU显著下降[平均减少(122.86±74.80)ml]。结论PAE治疗BPH有效、可行,具有良好的应用前景。

Objective To evaluate the feasibility and effectiveness of prostatic artery embolization（PAE）in treatment of benign prostatic hyperplasia（BPH）.Methods One month and 6 months after PAE,7 patients with BPH were reviewed and clinical results were collected.The changes of International Prostate Symptom Score（IPSS）,quality of life（QOL）,prostate volume（PV）,peak urinary flow（Q_（max））and residual urine（RU）before and after operation were observed and compared.Results A total of 12 prostate artery（PA）in 7 patients were treated with PAE.7 prostate artery originated from the inferior vesical artery,2 from the obturator artery,2 from the internal pudendal artery,1 from the inferior gluteal artery.Unilateral embolization was done in 2 cases,bilateral embolization in 5 cases.Compared with pre-operation,6 months after PAE,IPSS improved（24.00±3.90）points,QOL decreased（4.00±1.40）points,Q_（max）improved（8.45±1.90）ml/s,PV decreased（42.86±21.20）ml,RU decreased（122.86±74.80）ml.Conclusion PAE in treatment of BPH is effective and feasible,and has a good prospect of application.