三联疗法预防妇科腔镜术后恶心呕吐的疗效观察

Triple therapy to prevent gynecologic cavity mirror curative effect observation of postoperative nausea and vomiting

〔目的〕观察昂丹司琼、氟哌利多复合地塞米松（三联疗法）在妇科腔镜术后恶心呕吐（PONV）的预防疗效。〔方法〕择期全麻下行妇科腹腔镜手术患者120例,美国麻醉医师协会（ASA）分级为Ⅰ~Ⅱ级,术后均行PCEA（硬膜外镇痛）。随机分为3组（n=40）。A组单纯生理盐水组,B组昂丹司琼组,C组昂丹司琼＋地塞米松＋氟哌利多组。观察并记录患者术后24 h的恶心呕吐情况及不良反应。〔结果〕三组PONV发生率相比,A组〉B组〉C组,差异有统计学意义（P〈0.05）。〔结论〕三联疗法在妇科腔镜术后恶心呕吐方面有很好的预防疗效。

〔Objective〕To observe the Dan Si Qiong, droperidol compound dexamethasone（ triple therapy） in gynecologic cavity mirror effect prevention of postoperative nausea and vomiting（ PONV）. 〔Methods〕120 patients with elective general anesthesia downlink gynecological laparoscopic surgery, the American society of anesthesiologists（ ASA） class for Ⅰ ~ Ⅱ,postoperative PCEA in epidural analgesia. Randomly divided into 3 groups（ n = 40）. A purely physiological saline group, group B the Dan Si Qiong group, group C, Dan Si Qiong ＋ dexamethasone ＋ droperidol group. Observe and record patients postoperative nausea and vomiting and adverse reactions of 24 hours a day. 〔Results〕Three groups compared with the incidence of PONV, group A B C group, the difference was statistically significant（ P〈0. 05）. 〔Conclusion〕The triple therapy on postoperative nausea and vomiting of cavity mirrors of department of gynaecology have very good prevention effect.