天津市部分中老年人肥胖与牙周炎症相关性的调查

The correlation between obesity and periodontal inflammation in middle aged and elderly population in Tianjin City

目的：分析中老年人群肥胖与牙周炎症的相关性。方法：选择天津市某社区51-88岁中老年人321名,收集一般和全身情况信息,根据体质量指数将321名中老年人分成正常（124）、超重（136）、肥胖（61）3组,检测其血常规、总胆固醇、甘油三酯、低密度和高密度脂蛋白胆固醇等指标,检查牙周指标以及血清B细胞活化因子（BAFF）水平并进行统计分析。结果：3组人群的基本情况无差异,血常规指标均在正常范围内。空腹血糖、甘油三酯、总胆固醇、低密度脂蛋白及牙周指标中的菌斑指数、探诊深度、附着丧失在3组间无差异（P〉0.05）;而牙周出血指数、血清BAFF水平,肥胖组较正常组高（P〈0.05）;出血指数与BAFF水平呈正相关（P〈0.05）。结论：中老年人群中肥胖促进牙周炎症,血清BAFF可能参与了牙周炎症的调节过程。

AIM： To analyze the correlation between obesity and periodontal inflammation in middle aged and elderly population. METHODS： With informed consent,the general information of 321 middle aged and elderly subjects in one community of Tianjin City were collected. The subjects were divided into three groups： normal weight（ 124）,overweight（ 136） and obese（ 61） according to Body Mass Index（ BMI）. Also,the blood routine,total cholesterol,triglyceride,low density lipoprotein- cholesterol,high density lipoprotein- cholesterol,serum B cell activating factor（ BAFF） levels and periodontal inflammation index were examined. All the data were statistically analyzed. RESULTS： The general information was not statistically different among the 3 groups. Blood routine indexes were in the normal range. There was no significant difference among the 3 groups in the levels of fasting blood glucose,triglyceride,total cholesterol, low density lipoprotein- cholesterol, plaque index, probing depth and attachment loss（ P〉0. 05）. The periodontal bleeding index was significantly higher in the obese group（ P〈0. 05）. Serum BAFF levels were elevated in obese group compared with normal group（ P〈0. 05）. Bleeding index was positively correlated with serum BAFF levels（ P〈0. 05）. CONCLUSION： The obesity in middle aged and elderly people enhances periodontal inflammation,in which BAFF in serum may be involved.