高分辨磁共振血管壁成像在大脑中动脉粥样硬化疾病诊断中的应用

Clinical use of high-resolution magnetic resonance imaging for atherosclerosis of middle cerebral artery

在非白人人种中,颅内动脉粥样硬化疾病可能是最常见的缺血性卒中的病因。高分辨核磁成像的进展,使清晰显示大脑中动脉动脉管壁和斑块成分成为可能,并且高分辨核磁具有良好的观察者内和观察者间一致性。作为3D TOF MRA的补充,高分辨核磁能够弥补MRA的不足,从而能够发现MRA上无法发现的动脉粥样硬化斑块;颅内斑块的增强显像有可能用于识别斑块的易损性。在未来,对于高分辨核磁的影像表现和缺血事件发生的相关尚需要更多研究,它具有重要的临床意义。

Intracranial atherosclerotic disease may be the most common cause ofischemic stroke in non-Western populations. Advances in high-resolution MR imaging of MCA stenosis have the potential to yield excellent visualizatinn of the arterial wall and plaque constituents of middle cerebral arteries, which shows good inter- and intraobserver reproducibility. As a complementary method, it may make up for the limitation of 3D TOF MRA and help to detect atherosclerotic lesions not visualized by MRA. The enhancement of intracranial plaque could potentially be used to indicate vulnerability. Additional work to correlate imaging findings with risk of future outcomes is necessary to offer clinical significance.