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急性早幼粒细胞白血病治疗方案的优化研究 被引量:4

Discussion about optimizing treatment of acute promyelocytic leukemia
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摘要 急性早幼粒细胞白血病(APL)是急性髓系白血病的亚型之一。超过95%的APL患者15号染色体的PML基因与17号染色体的RARA基因发生融合形成PML-RARA融合基因,其产生的融合蛋白导致髓系细胞分化障碍并停滞住早幼粒细胞阶段。
作者 李森 王书杰
出处 《中国实用内科杂志》 CAS CSCD 北大核心 2016年第4期329-331,共3页 Chinese Journal of Practical Internal Medicine
基金 卫生公益性行业科研专项经费项目(201202017)
关键词 急性早幼粒细胞 全反式维甲酸 三氧化二砷 去化疗 acute promyelocytic leukemia all-trans retinoic acid arsenic trioxide chemotherapy-flee
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