天津汉族帕金森病患者VPS35基因Asp620Asn突变的筛查
摘要
目的对天津汉族帕金森病（Parkinson’sdisease，PD）患者和正常对照的VPS35基因c．1858G〉A（p．Asp620Asn）突变进行筛查。方法收集散发PD患者330例，对照组250名的临床资料并提取基因组DNA。采用病例一对照方式研究，应用SNapShot技术检测患者及对照组的VPS35基因Asp620Asn突变情况。结果在PD组和对照组均未发现VPS35Asp620Asn突变。结论VPS35Asp620Asn并非天津汉族帕金森患者的突变位点。
出处
《中华医学遗传学杂志》
CAS
CSCD
北大核心
2016年第2期261-263,共3页
Chinese Journal of Medical Genetics
参考文献13
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