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微小RNA与卵巢癌关系的研究进展 被引量:9

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摘要 卵巢癌(ovarian cancer)是严重威胁女性健康的恶性肿瘤之一,其发病率在女性生殖器恶性肿瘤中仅次于宫颈癌和子宫内膜癌,位居第三,但病死率却高居首位。卵巢癌在早期并无特异性临床表现,大部分患者确诊时已发生癌细胞的转移、侵袭,近期文献报道卵巢癌的5年生存率为42.9%,但超过80.0%的晚期卵巢癌患者会复发,且预后极差[1]。
出处 《重庆医学》 CAS 北大核心 2016年第10期1407-1409,共3页 Chongqing medicine
基金 云南省教育厅科研基金重点项目(2014Z075)
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  • 1Yeh CN,Pang ST,Chen TW,et al.Expression of ezrin is associated with invasion and dedifferentiation of hepatitis B related hepatocellular carcinoma.BMC Cancer,2009,9:233.
  • 2Chuan YC,Iglesias-Gato D,Fernandez-Perez L,et al.Ezrin mediates c-Myc actions in prostate cancer cell invasion.Oncogene,2010,29:1531-1542.
  • 3Valdman A,Fang X,Pang ST,et al.Ezrin expression in prostate cancer and benign prostatic tissue.Eur Urol,2005,48:852-857.
  • 4Karmakar S,Das C.Modulation of ezrin and E-cadherin expression by IL-1 beta and TGF-beta1 in human trophoblasts.J Reprod Immunol,2004,64:9-29.
  • 5Moilanen J,Lassus H,Leminen A,et al.Ezrin immunoreactivity in relation to survival in serous ovarian carcinoma patients.Gynecol Oncol,2003,90:273-281.
  • 6Chen Z,Fadiel A,Feng Y,et al.Ovarian epithelial carcinoma tyrosine phosphorylation,cell proliferation,and ezrin translocation are stimulated by interleukin lalpha and epidermal growth factor.Cancer,2001,92:3068-3075.
  • 7Song J,Fadiel A,Edusa V,et al.Estradiol-induced ezrin overexpression in ovarian cancer:a new signaling domain for estrogen.Cancer Lett,2005,220:57-65.
  • 8K(o)bel M,Gradhand E,Zeng K,et al.Ezrin promotes ovarian carcinoma cell invasion and its retained expression predicts poor prognosis in ovarian carcinoma.Int J Gynecol Pathol,2006,25:121-130.
  • 9Lewis BP,Burge CB,Bartel DP.Conserved seed pairing,often flanked by adenosines,indicates that thousands of human genes are microRNA targets.Cell,2005,120:15-20.
  • 10Livak KJ,Schmittgen TD.Analysis of relative gene expression data using real-time quantitative PCR and the 2 (-Delta Delta C (T)) Method.Methods,2001,25:402-408.

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