声脉冲辐射力成像对乳腺良恶性结节的鉴别诊断价值

Value of acoustic radiation force impulse imaging in diagnosis of benign and malignant breast lesions

目的 :探讨声脉冲辐射力成像(acoustic radiation force impulse,ARFI)在诊断乳腺良恶性结节中的价值。方法:分析128例共145个经病理证实的乳腺结节的声脉冲辐射力成像特征。采用ROC曲线评价剪切波速度值对乳腺病灶良恶性的鉴别诊断价值,并确定临界值。结果:145个结节中,良性结节107个,恶性结节38个。乳腺病灶良性组与恶性组的剪切波速度(shearwave velocity,SWV)值分别为(2.89±1.13)m/s和(6.57±1.36)m/s,2组差异有统计学意义(P<0.05)。以SWV值3.37 m/s为临界值诊断乳腺病灶的良恶性的敏感度、特异度、准确度分别为89.4%、89.7%、90.3%。结论:ARFI为乳腺结节的良恶性鉴别诊断提供了新的分析方法,具有重要的临床价值。

Objective：To explore the value of acoustic radiation force impulse （ARFI） imaging in the diagnosis of benign and malignant breast lesion. Methods：Analysed the features of ARFI of 128 cases with 145 breast lesions which confirmed by pathology. The cut-off values were determined by the analysis of receiver-operating characteristic （ROC） curve using pathology as the golden criteria. Results：There were 107 benign lesions and 38 malignant lesions in 145 lesions.The shear-wave velocity （SWV） value of benign and malignant breast lesions were （2.89 ± 1.13）m/s and（6.57 ± 1.36）m/s. There was significant difference in the SWV value between benign and malignant breast lesions （P〈0.05）. When the diagnostic threshold was 3.37m/s,the sensitivity,specificity and accuracy of SWV values between benign and malignant breast lesion was 89.4%,89.7%,90.3%,respectively. Conelusion：ARFI provides a new analysis method for the differential diagnosis of benign and malignant breast lesions,and has important clinical value.