烟酸类表面活性剂的合成研究

Synthesis of Niacin Surfactants

以烟酸为原料,通过卤置换反应、酰胺化反应、季铵化3步反应,合成[3,3'-(对苯二氨甲酰基)]双N-烷基吡啶溴盐表面活性剂目标产物。用IR、1HNMR、13CNMR和MS对目标产物进行确认和表征,并通过单因素试验,确定了较佳的合成条件:n(双(烟酰基)对苯二胺)∶n(溴代烷)=1∶2.6,反应温度140℃,反应时间6 h。利用紫外分光光度法测量目标产物的临界反胶团浓度CrMC分别为2.09×10-5、2.27×10-5和2.39×10-5mol/L。

A series of [3,3＇-（ p-phenyldiaminocarbonyl） ]bis（ N-alkyl） pyridinium bromide surfactants products were prepared by chloride displacement,amidation and quaterisation. The structure of products was confirmed by IR,1HNMR,13 CNMR and MS. The reaction temperature was 140 ℃,the reaction time was 6 h,the mole ratio of intermediate bis（ nicotinoyl） p-phenylenediamine and bromoalkane was 1∶ 2. 6. The critical reverse micelle concentration（ CrMC） of the target products are 2. 09 × 10- 5,2. 27 ×10- 5,2. 39 × 10- 5mol / L by UV spectrophotometer measurement respectively.