清瘟败毒饮对脓毒症患者血乳酸和胱抑素C影响的临床观察

Clinical Observation of the Influence of Qingwen Baidu Decoction on the Clearance Rate of Cys-C and Blood Lactate in Patients with Sepsis

目的:观察中药复方清瘟败毒饮对脓毒症患者血乳酸和胱抑素C的影响。方法:将75例脓毒症患者按随机数字表法分为清瘟败毒饮中西医结合治疗组(治疗组38例)和西医治疗组(对照组37例),治疗组在西医常规治疗方法基础上加中药清瘟败毒饮治疗,对照组给予西医常规方法治疗,观察2组患者治疗7 d的临床疗效,以及治疗3 d、7 d后血清胱抑素C和血乳酸水平变化情况。结果:治疗组在提高临床控制率、改善中医症状积分和APACHEⅡ评分方面优于对照组,并有显著降低血清胱抑素C和血乳酸水平作用。结论:应用清瘟败毒饮中西医结合治疗脓毒症可降低患者血乳酸水平,保护肾脏等重要脏器,具有进一步提高临床疗效作用。

Objective： To observe the influence of Qingwen Baidu Decoction on the clearance rate of cys-C and blood lactate in patients with sepsis. Methods： 75 cases of sepsis patients in our hospital, were randomly divided into the application of Qingwen Baidu Decoction in the combination therapy group （treatment group, n = 38） and Western medicine group （control group, n = 37）. The treatment group treated by routine western medicine plus Qingwen Baidu Decoction, the control group were treated with routine therapy, to evaluate the therapeutic effect, changes of cys-C and blood lactate clearance rate after treatment 3,7 days. Results： In the aspect of significant efficiency, improve the TCM syndrome score and APACHE Ⅱ score, the treatment group was better than the control group, in the lower cys-C and blood lactate level, the treatment group has an advantage. Conclusion： Qingwen Baidu Decoction combined with western medicine in the treatment of sepsis, can further enhance the clinical curative effect, protect the function of important organs.